This 116-page resource guides the reader through the process of determining if an innovation (defined here as a new approach to health care delivery, whether device or process or approach) is appropriate and feasible for their institution. The guide is divided into four modules presented as questions: 1) does the innovation fit? 2) should we do it here? 3) can we do it here? and 4) how will we do it here? Additional resources and case studies are also included. This tool would likely be of greatest interest to health care providers and system administrators.