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Plasma Fibrinogen as a Biomarker for Mortality and Hospitalized Exacerbations in People with COPD

Resource Type: Research Papers

The COPD Biomarkers Qualification Consortium (CBQC) is a partnership between the COPD Foundation, the U.S. Food and Drug Administration (FDA) and the pharmaceutical industry developed in part to demonstrate that individual biomarkers can be used effectively in the drug development process. This paper presents the process and outcomes of a project seeking approval of fibrinogen, a measure of inflammation, as a biomarker for use in clinical COPD trials.

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Mannino DM, Tal-Singer R, Lomas DA, et al. Plasma fibrinogen as a biomarker for mortality and hospitalized exacerbations in people with COPD. J COPD F. 2015; 2(1): 23-34. Accessed March 19, 2020.

exacerbations hospitalization

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