COPD Foundation Nebulizer Consortium (CNC)

There is currently inconclusive scientific evidence that nebulizer treatments increase transmission of coronaviruses (or other infectious disease agents). We believe that further research is needed to explore this very important topic related to coronavirus 2019 (COVID-19) and other airborne illnesses.

The COPD Foundation Nebulizer Consortium (CNC) aims to improve the understanding of any infection risks that may be associated with the administration of nebulized therapies and to develop solutions that ensure the safety of patients, caregivers, and health care providers.

The CNC aims to improve the understanding of any infection risks that may be associated with the administration of nebulized therapies and to develop solutions that ensure the safety of patients, caregivers, and health care providers.

What areas are we focusing on?

research

Research: Includes basic science, clinical and patient-focused projects, and publication of relevant findings.


education

Education: raise community awareness on nebulizer use in the COVID-19 environment and provide useful information to health care providers and those living with or caring for people with respiratory diseases.


guidance

Guidance: We will work with stakeholders to develop and promote guidelines for nebulizer use in various settings, including recommendations for health care providers.


The COPDF will apply COPD360 tools including COPD360social, and COPD Patient-Powered Research Network (PPRN), PRAXIS and other community outreach methods to provide information on the use of nebulizers during the COVID-19 pandemic or other respiratory infections.

Examples of initiatives may include:

  • Collaborating with researchers assessing potential production of virus containing aerosols with nebulizer use in the inpatient, outpatient, and home settings.
  • Gathering data from patients, caregivers, and health care professionals through focus groups and/or surveys to understand concerns and impact, if any, on current medication use.
  • Developing educational materials designed to explain possible aerosol-mediated infection risks and risk mitigation strategies for nebulizer users.

Who are the members of the Consortium?

The COPD Foundation (COPDF) led Nebulizer Consortium is comprised of industry members, many scientific and academic field experts, and one government representative.


CNC Structure

CNC Structure

CNC COPDF members include:

  • David Mannino, MD, Co-Founder and Medical Director (CNC COPDF Co-chair)
  • Ruth Tal-Singer, PhD, President and Chief Scientific Officer
  • Elisha Malanga, BS, Chief Research Officer
  • Debora Merrill, MBA, Vice President, COPD Biomarkers Qualification Consortium and Project Management
  • Mike Hess, MPH, RRT, RPFT, Senior Director of Public Outreach and Education
  • Julie Yates, BS, Senior Director COPD360 Clinical Investigations
  • Sergio Martinez, Project Manager for Research

Patient Advocates:

  • Dan Kealing, COPD Foundation Texas State Captain
  • Bonnie Truelsen, COPD Foundation Illinois State Captain
  • Diane Walsh, COPD Foundation Missouri State Captain

Current CNC industry members include:

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  • Karmon Johnson, PharmD (CNC Industry Co-chair)
  • Lauren Cochran, PharmD

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  • Lisa Cambridge, MSHS, RRT
  • Rosina Ledermueller
  • Michael Hahn
  • Nicholas Schwenck

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  • Patricia A Dailey, MSc, RRT
  • Brant Nave

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  • Jason Suggett, PhD, BPharm, MBA
  • Dom Coppolo, MBA, RRT, FAARC, AE-C
  • Judy Schloss

Current CNC scientific/academic members include:

  • Phil Kuehl, PhD, Lovelace Biomedical
  • David C. Christiani, MD, MPH, MS, Harvard Medical School; Massachusetts General Hospital
  • Igor Barjaktarevic, MD, PhD, University of California Los Angeles
  • Jill Ohar, MD, Wake Forest University
  • Jie Li, PhD, RRT-NPS, RRT-ACCS, FAARC, Rush University
  • M. Brad Drummond, MD, MHS, University of North Carolina at Chapel Hill
  • Donald Mahler, MD, Valley Regional Hospital, Claremont, New Hampshire; Professor Emeritus at Dartmouth College
  • Rajiv Dhand, MD, FCCP, FACP, FAARC, FRSM, ATSF, University of Tennessee Health Sciences Center
  • Akshay Sood, MD, MPH, University of New Mexico School of Medicine
  • Arzu Ari, PhD, RRT, PT, CPFT, FAARC, FCCP, Texas State University
  • Sanjay Sethi, MD, University at Buffalo, State University of New York
  • Brian Carlin, MD, Sleep Medicine and Lung Health Consultants, Pittsburgh, PA
  • Donald Tashkin, MD, University of California Los Angeles
  • Lisa Saunders, BAS, RRT, TTS, Kalamazoo, MI

Government liaison member:

  • Lewis J. Radonovich, MD, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Resources for Human Development agency

References to publicly-available publications

For a list of references please contact Sergio Martinez, Project Manager at smartinez@copdfoundation.org.

  • Viral Transmission of Respiratory Pathogens
  • Aerosol-Generating Procedures
  • Evidence Evaluating Coronavirus Transmission via Nebulization
  • Safe Administration of Nebulized Therapies in the COVID-19 Era
  • Aerosol-Generating Procedures
  • Evidence Evaluating Coronavirus Transmission via Nebulization
  • Safe Administration of Nebulized Therapies in the COVID-19 Era

Abbreviation Listplus

  • AARC: American Association for Respiratory Care
  • AGP: aerosol-generating procedure
  • AIIR: airborne infection isolation room (negative pressure room)
  • ATS: American Thoracic Society
  • BAN: breath-actuated nebulizer
  • BEN: breath-enhanced nebulizer
  • BiPAP: bilevel positive airway pressure
  • CDC: Centers for Disease Control and Prevention
  • CHEST: American College of Chest Physicians
  • CI: confidence interval
  • COVID-19: coronavirus disease 2019
  • CPAP: continuous positive airway pressure
  • CPR: cardiopulmonary resuscitation
  • DPI: dry-powder inhaler
  • H1N1: subtype of influenza A
  • HCP: healthcare professional
  • HCW: healthcare worker
  • HFNC: high flow nasal cannula
  • IDSA: Infectious Diseases Society of American
  • JN: jet nebulizer
  • MDI: metered-dose inhaler
  • MERS: Middle Eastern respiratory syndrome
  • MERS-CoV: Middle Eastern respiratory syndrome coronavirus
  • MIP: maximum inspiratory pressure
  • FEV1: forced expiratory volume in 1 second
  • N95: N95 respirator, respirator blocks at least 95% of very small test particles
  • NIH: National Institutes of Health
  • PAPR: powered air-purifying respirator
  • PIFR: peak inspiratory flow rate
  • PPE: personal protective equipment
  • Ro: R naught, indication of how contagious an infectious disease is
  • SARS: severe acute respiratory syndrome
  • SARS-CoV-1: severe acute respiratory syndrome coronavirus 1
  • SARS-CoV-2: severe acute respiratory syndrome coronavirus 2
  • SMI: soft-mist inhaler
  • VMN: vibrating mesh nebulizer
  • WHO: World Health Organization
  • μm: micrometer (micron)

What has the CNC achieved thus far?

COPD Foundation Nebulizer Consortium | Nebulizers, COVID-19, and You!

Nebulizers, COVID-19, and You!

January 29, 2021

We know that nebulizers are the cornerstone of treatment for chronic lung conditions such as COPD, bronchiectasis, NTM, and asthma. The COVID-19 pandemic has brought about new questions and concerns about using nebulizers in health care clinics or hospitals and for some, even at home.

The COPD Foundation has partnered with academic experts, industry partners, and other stakeholder groups to create the COPD Foundation Nebulizer Consortium (CNC) to develop research and education practices related to safe nebulizer use.

Watch this Facebook Live event where COPD Foundation's Mike Hess, RRT, David Mannino, MD and Janice Cotton, BS, MA (COPD Foundation Illinois State Captain) discussed nebulizer use in the age of COVID-19 and the formation of the COPD Foundation Nebulizer Consortium (CNC).

How can a company join the CNC?

The COPD Foundation has invited pharmaceutical companies and nebulizer device manufacturers to join this important effort. To join the CNC, a company will sign the CNC Agreement, pay a membership fee and join working groups of interest, aligned with interests and expertise. Members will share costs of CNC-approved projects.

Interested in joining the CNC?

Contact:
Sergio Martinez, Project Manager
smartinez@copdfoundation.org