COPD PPRN to Participate in $4 Million Research Study Comparing Stress Management Approaches

WASHINGTON, D.C. - July 26, 2017 - A team of patient and stakeholder partners and investigators from 20 Patient-Powered Research Networks (PPRNs) that comprise PCORnet will take part in a $4 million research project, Healthy Mind Healthy You, to determine the optimal type and frequency of mindfulness-based treatment for managing stress. This project will be under the leadership of MoodNetwork, an online network for patients with bipolar disorder and depression. MoodNetwork, based at Massachusetts General Hospital (MGH), is one of 20 PCORI-funded Patient-Powered Research Networks (PPRNs) participating in this study, which will also demonstrate the capabilities of PCORnet, the National Patient-Centered Clinical Research Network.

An ambitious initiative funded by the Patient-Centered Outcomes Research Institute (PCORI), PCORnet is accelerating the nation’s ability to conduct patient-centered clinical research more efficiently by using health information shared by patients and other clinical data. PPRNs, which are collaborations among patients, other stakeholders, and research partners who share an interest in advancing patient-centered research, comprise 20 of the 33 networks that together make up PCORnet.

Healthy Mind Healthy You will randomly assign participants across more than 100 conditions to a “light” (3-session) or “standard” (8-session) online mindfulness-based intervention to determine which treatment is most helpful for improving well-being. This topic has been recognized as a top priority area for comparative effectiveness research by the Institute of Medicine and has the potential to inform patients, caregivers, and clinicians as to the most effective dose of mindfulness for stress and wellness management. This study will be led by a team of active stakeholder and patient partners across the 20 patient powered research networks.

“This study will not only help people determine the right amount of mindfulness that could help them cope better with stress, but will also demonstrate how the 20 PPRNs can combine their expertise to improve the lives of people across over 100 conditions and understudied populations,” said Andrew A. Nierenberg, M.D., Principal Investigator of the MoodNetwork and Director of the Bipolar Clinic and Research Program at MGH.

PCORI provided the funds to support this research project. The funding award has been approved pending completion of a business and programmatic review by PCORI staff and issuance of a formal award contract.

PCORI is an independent, nonprofit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers, and clinicians with the evidence-based information needed to make better-informed healthcare decisions. For more information about PCORI’s funding, visit